Chief, Michiru Makuuchi, Ph.D.
makuuchi-michirurehab.go.jp /
【CV(pdf)】
Our research focus is the brain mechanisms of language. Understanding the function of Broca's area is a key to our research question. Broca's area is known to play an important role in production of speech, but lesion confined to this area does not cause aphasia. Instead, it causes effortful articulation which lasts only for a limited period. To our surprise, modern neuroimaging methods have revealed that Broca's area is involved in various cognitive tasks including hand/finger movement, drawing, music perception, visual rhythm perception, arithmetic, etc. beyond speech production. The range of cognitive tasks that Broca's area is involved is so wide, that the exact role of this area becomes even more elusive. We aim at finding an account for this enigma using neuroimaging techniques such as fMRI, EEG, and TMS. The results will provide a basis for developing rehabilitation methods for aphasics and people with cognitive impairments.
Left: Broca's and Wernicke's areas shown on the left hemisphere. Right: A finite state automaton for artificial grammar learning experiments.
Toshiki Iwabuchi, Ph.D.
Postdoctoral researcher / iwabuchi-toshikirehab.go.jp
The aim of my research is to contribute to develop new rehabilitation techniques or training methods for persons with cognitive disabilities by elucidating the brain mechanisms underlying aphasia or higher brain dysfunctions. I am engaged in research on interactions between language and other cognitive functions such as cognitive control or working memory, using functional magnetic resonance imaging (fMRI), electroencephalography (EEG), and transcranial magnetic stimulation (TMS).
【 close 】
【Professional experience】
| April, 2014-present |
Postdoctoral researcher, Research Institute of National Rehabilitation Center for Persons with Disabilities, Saitama, Japan |
| April, 2013-March, 2014 |
Research fellow, Graduate School of Informatics, Kyoto University, Kyoto, Japan |
| April, 2011-March, 2013 |
JSPS research fellow, Japan Society for the Promotion of Science, Tokyo, Japan |
【Education】
Graduate School of Informatics, Kyoto University, Kyoto, Japan
Doctor of Informatics, March, 2013
【Publications】
Original papers in English
1). Toshiki Iwabuchi, Masato Ohba, Toshio Inui, & Kenji Ogawa (2011) An fMRI investigation of the mental perspective shift in language comprehension. In Wang, R. & Gu, F. (eds), Advances in Cognitive Neurodynamics (II) (pp.351-354). Dordrecht: Springer.
2). Toshiki Iwabuchi, Toshio Inui, Masato Ohba, & Kenji Ogawa (2011) Neural basis of the shift in grammatical subject: A functional magnetic resonance imaging study. Proceedings of 2011 IEEE/ICME International Conference on Complex Medical Engineering, 520-525.
3). Toshiki Iwabuchi, Toshio Inui, Masato Ohba, & Kenji Ogawa (2013) A functional MRI study of a picture-sentence verification task: evidence of attention shift to the grammatical subject. NeuroReport, 24, 298-302.
International conferences
1). Toshiki Iwabuchi, Masato Ohba, Toshio Inui, & Kenji Ogawa. (2009) An fMRI investigation of the mental perspective shift in language comprehension. The 2nd International Conference on Cognitive Neurodynamics (ICCN 2009), 15-19 November, Hangzhou, China.
2). Toshiki Iwabuchi, Toshio Inui, Masato Ohba, & Kenji Ogawa. (2011) Neural basis of the shift in grammatical subject: A functional magnetic resonance imaging study. 2011 IEEE/ICME International Conference on Complex Medical Engineering, 22-25 May, Harbin, China.
3). Toshiki Iwabuchi, Toshio Inui, & Kenji Ogawa. (2012) Cortical mechanisms underlying the processing of Japanese hierarchically embedded sentence structure. The Fourth Annual Neurobiology of Language Conference (NLC 2012), 25-27 October, San Sebastian, Spain.
4). Toshiki Iwabuchi, Toshio Inui, & Kenji Ogawa. (2013) The cortical mechanisms for the processing of hierarchical structure in comprehension of complex sentences: An fMRI study. Neuro2013, 20-23 June, Kyoto, Japan.
Tomomi Mizuochi-Endo, Ph.D.
JSPS Research Fellow /
mizuochi-tomomirehab.go.jp
The aim of my research is to cite scientific evidence for rehabilitation of patients with aphasia or higher brain dysfunctions. Especially, I want to investigate integration process of auditory and other modality (visual, motor and so on) information, using functional magnetic resonance imaging (fMRI), electroencephalography (EEG), and transcranial magnetic stimulation (TMS).
【 close 】
【Professional experience】
| April, 2014-present |
Visiting Researcher, Special appointment Employee, Laboratory for Language Development, RIKEN BSI, Saitama, Japan
|
| April, 2011-present |
Research Fellow of the Japan Society for the Promotion of Science (PD),Tokyo, Japan |
| May, 2009-March, 2011 |
Research Scientist, Special appointment Employee, Laboratory for Language Development, RIKEN BSI, Saitama, Japan |
| April, 2009 |
Research Scientist, Special appointment Employee, Department of Otolaryngology, Graduate school of Medicine, University of Tokyo |
| April, 2006-March, 2009 |
Research Fellow of the Japan Society for the Promotion of Science (DC1),Tokyo, Japan |
【Education】
Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Doctor of Medicine, March, 2009
【Publications】
Original papers in English
1). Mizuochi Tomomi, Yumoto Masato , Karino Shotaro , Itoh Kenji , Yamakawa Keiko, Kaga Kimitaka (2005) Effect of the spectral envelope on the auditory evoked N100m, International Congress Series, Volume 1278, Pages 247-250
2). Mizuochi Tomomi, Yumoto Masato , Karino Shotaro , Itoh Kenji , Yamakawa Keiko , Kaga Kimitaka (2005) Perceptual categorization of sound spectral envelopes reflected in auditory-evoked N1m, Neuroreport, 16(6), 555-558.
3). Karino Shotaro , Yumoto Masato, Itoh Kenji, Yamakawa Keiko, Mizuochi Tomomi, Kaga Kimitaka (2005) A modified parallel paradigm for clinical evaluation of auditory echoic memory, Neuroreport, 16(7), 683-688.
4). Mizuochi Tomomi, Yumoto Masato , Karino Shotaro , Itoh Kenji , Yamakawa Keiko , Kaga Kimitaka (2007) Categorical perception of timbre reflected in the latency of auditory evoked N100m, Clinical Neurophysiology, 118(9), e194-e195.
5). Mizuochi Tomomi, Yumoto Masato, Karino Shotaro, Itoh Kenji, Tatsuya Yamasoba (2007) Latency variation of auditory N1m responses to vocal and nonvocal sounds, Neuroreport, 18(18), 1945-1949.
International conferences
1). Karino Shotaro , Yumoto Masato , Itoh Kenji , Yamakawa Keiko , Mizuochi Tomomi ,Kaga Kimitaka (2004) A modified parallel paradigm for clinical evaluation of auditory echoic memory using magnetoencephalography, The 8th International Evoked Potential Symposium, Fukuoka, Japan The 8th International Evoked Potential Symposium
2). Mizuochi Tomomi, Yumoto Masato , Karino Shotaro , Itoh Kenji , Yamakawa Keiko , Kaga Kimitaka (2004) Effect of the spectral envelope on the auditory evoked N100m, The 8th International Evoked Potential Symposium, Fukuoka, Japan
3). Mizuochi Tomomi, Yumoto Masato , Karino Shotaro , Itoh Kenji , Yamakawa Keiko , Kaga Kimitaka (2006) Categorical perception of timbre reflected in the auditory evoked N100m, 12th Annual Meeting Human Brain Mapping, Firenze, Italy
4). Yumoto Masato , Itoh Kenji , Karino Shotaro , Ogata Erika, Mizuochi Tomomi Yu Yatomi (2006) A motor-to-sound oddball paradigm revealed top-down modulation of auditory perception in a multimodal predictive context, 28th International Congress of Clinical Neurophysiology Edinburgh, Scotland
5). Mizuochi Tomomi, Yumoto Masato , Karino Shotaro , Itoh Kenji , Yamakawa Keiko , Kaga Kimitaka (2006) Steady-sound spectral perception reflected in auditory-evoked N1m, 17th Meeting International Society for Brain Electromagnetic Topography, Chiety, Italy
6). Mizuochi Tomomi , Yumoto Masato , Karino Shotaro , Itoh Kenji , Yamasoba Tatsuya (2008) F0 independency of auditory evoked N1m is vocal sound specific?, 14th Annual Meeting Human Brain Mapping, Melbourne, Australia
7). Mizuochi Tomomi , Yumoto Masato , Karino Shotaro , Itoh Kenji , Tatsuya Yamasoba (2008) Categorical perception of timbre shapes the auditory-evoked N1m, 16th International Conference on Biomagnetism, Sapporo, Japan
8). Mizuochi-Endo Tomomi , Oishi Hiroaki, Omori Risako, Tsuji Sho, Hasegawa Mihoko, Mazuka Reiko (2011) A developmental transition in infants' mismatch response to sound duration change, 17th Annual Meeting Human Brain Mapping, Qu?bec, Canada
9). Carline Bernard, Tomomi Mizuochi-Endo, Hiroaki Oishi, Reiko Mazuka, Judit Gervain (2014) Eight-month-old infants' acquisition of word order: a French-Japanese cross-linguistic ERP study, BCCCD 2014 Budapest CEU Conference on Cognitive Development, Budapest, Hungary
【Award】
2007 The U35 Best paper award
(Annual Meeting of Japan Biomagnetism and Bioelectromagnetics Society)
2008 Young Investigator Award
(International Conference on Biomagnetism)
【Funding】
2006-2008FY Grant-in-Aid for JSPS Fellows
2010FY Grant-in-Aid for Young Scientists (B)
2011-2014FY Grant-in-Aid for JSPS Fellows
2014-2017FY Grant-in-Aid for Young Scientists (B)
Former Members
Kimihiro Nakamura
Section chief, Jan 2011 - Aug 2011.
Current position: Human Brain Research Center,
Graduate School of Medicine, Kyoto University, Kyoto, Japan
Kaori Yamaguchi
Postdoctoral Research fellow, Jun 2011 - May 2012.
Current position: Information and Support Center for Persons with Developmental Disorders
National Rehabilitation Center for Persons with Disabilities, Tokorozawa, Japan